CCR5-delta32
About 1% of people of Northern European descent carry two copies of a broken gene that makes them almost immune to the most common form of HIV. A bone marrow transplant from one such donor produced the first cure of HIV.
Genetics, development, and things that involve the whole organism.
12 oddities. 3 have this as their primary region.
About 1% of people of Northern European descent carry two copies of a broken gene that makes them almost immune to the most common form of HIV. A bone marrow transplant from one such donor produced the first cure of HIV.
A chimera is one person made of two sets of cells with different DNA. It happens when two embryos fuse in the first days of pregnancy. Most chimeras never find out. A few discovered it when a DNA test said they were not the mother of their own children.
A tiny number of people are born unable to feel pain. Single-gene changes switch off their pain nerves. It is not a superpower. Injuries go unnoticed, and most people with it are badly hurt in childhood.
A widening of the gap between the two halves of the six-pack muscle, seen in nearly every pregnancy and in some men. A bulge down the midline when you sit up is the usual sign.
Touching the tip of your nose with your tongue. About 10% of people can do it. About half of people with Ehlers-Danlos syndrome can, so doctors use it as a quick check for stretchy connective tissue.
About 1 in 5 people have joints that bend further than usual, measured with a nine-point test called the Beighton score. For most people it causes no trouble.
A foot that bends in the middle, between the heel and the ball, as well as at the toes. About 1 in 13 people have it. It is a leftover from tree-climbing ancestors.
A small number of people need only 4 to 6 hours of sleep a night, wake without an alarm, and feel fine. Several gene variants that cause it have been found. Most people who sleep that little are simply sleep-deprived.
All the organs in the chest and belly sit on the opposite side from usual, as in a mirror. About 1 in 10,000 people are built this way, and most are healthy.
An extra nipple, usually small and flat, on a line running from the armpit to the groin. Between 1 in 500 and 1 in 18 people have one, and most think it is a mole.
Most people have three kinds of colour-sensing cone. A few people have four. In theory they can tell apart colours that look identical to everyone else. Confirmed cases are extremely rare, and online tests cannot detect it.
Pushing a joint partly or fully out of its socket on purpose, then back in. About 20% of people have some joint hypermobility. True voluntary dislocation is much rarer and often linked to a connective tissue disorder.